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Nov 13, 2015 21:46
8 yrs ago
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Russian term

безлинейные крысы

Russian to English Science Medical: Pharmaceuticals research of a medicine
эксперимент проведен на 10 белых безлинейных крысах с массой тела 180-200 г.

outbred rats?

заранее спасибо!
Proposed translations (English)
5 random-bred rats
4 +3 mongrel rats

Discussion

Jack slep Nov 15, 2015:
Jennifer, I Goggled again and got 3 (three!), 19,200,000, and 21,000,000 random-breds. They are either breeding quickly or dying off rapidly depending on how you look at it. Yes, mongrel to me was always a dog or a mean nextdoor neighbor. But there are also mongrel vegetables--I'll let you try them. I, too, gor for "random-bred" (rat, mice, chicken, stock, population, etc.).
Jennifer Guernsey Nov 15, 2015:
I got ~4000 results to that query, though the number is pretty immaterial here. I think "random-bred" is better, because "outbred" is still associated with specific strains/breeds, e.g., "outbred Wistar rats". "Random-bred" seems to be more truly "breedless". But you can still go with "mongrel" if you're talking about research dogs. ;)

My scientist folks have not been much help...have heard from only one thus far, and she suggested outbred. She said in older literature they would just say things like "white laboratory rats". Sounds like they don't encounter/use "breedless" strains much anymore, at least not in the US.
Jack slep Nov 15, 2015:
Arabella, in Google there are 21 million eferences to Charles River random-bred animals. However, research shows in my mouse genetic book that "A large number of the laboratory mice sold and used by investigators around the world are considered to be outbred or random-bred. Popular stocks of such mice in the U. S. include CD-1 (Charles River Breeding Laboratories), Swiss Webster (Taconic Farms), and ICR and NIH Swiss (both from Harlan Sprague Dawley). " Consquently, either term is correct.
Jennifer Guernsey Nov 15, 2015:
I don't think "outbred" works either. I'm looking at the website of Charles River Labs http://www.criver.com/find-a-model?animal_type=Rats
and they have, e.g., Wistar rats that are listed as outbred. So "outbred" is clearly not "breedless".
Jennifer Guernsey Nov 15, 2015:
Hey Jack! You may well be right about mongrel, though that's the only term I can recall running across. I'm not too sure about random-bred, though, either. When I search PubMed for mongrel, I get 72 hits, all translations...when I search for random-bred, I get 40 hits, also all apparent translations (some Russian, lots of Italian). I've put out a query to a few of my researcher friends...will let you know what they say.
Jack slep Nov 15, 2015:
Arabella, with all due respect young lady, your profile shows little in knowledge of life sciences, nothing aboiut rats or any research involved with them or any other lab animal. Strains have been developed for all types of diseases, but sometimes you need just a plain old lab rat/animal. If you're determined to use "outbred," then research the Russian term for which; furtherrmore, don't send me a long obviously copied dissertation on genetics to prove or disprove a point, a subject about which you have little or no knowledge. If you don't know the terminology, you don't know the subject. This is not a criticism, just advise from an old (85 yr) R>E translator for 65 years of 70 different Russian journals, learn the subject, the terminiology therein. You may never understand the subject matter e.g., magnetohydrodynamics, but if you learn the lexicon you'll simultaneously learn it, perhaps only superficially, but still offer an intelligent translation.What answer you select to your question is of little consequence to me, my point being to you, a "freshman/woman" translator, is your own research and don't believe everything you get in reply, including mine. Best luck as a profession
Arabella Bishop (asker) Nov 14, 2015:
http://www.janvier-labs.com/rodent-research-models-services/...
Arabella Bishop (asker) Nov 14, 2015:
I just don't want to disappoint my client with wrong terminology, you know :)
Arabella Bishop (asker) Nov 14, 2015:
one more from UK: http://www.3rs-reduction.co.uk/html/8__strains_of_mice.html
Arabella Bishop (asker) Nov 14, 2015:
Description in Russian: http://www.pravda.ru/science/04-02-2009/300688-mouse-0/
Arabella Bishop (asker) Nov 14, 2015:
Is it not the same: Systematic inbreeding and maintenance of inbred strains of laboratory mice and rats is of great importance for biomedical research. The inbreeding guarantees a consistent and uniform animal model for experimental purposes and enables genetic studies in congenic and knock-out animals. The use of inbred strains is also important for genetic studies in animal models, for example to distinguish genetic from environmental effects. The mice that are inbred typically show considerably lower survival rates.

Proposed translations

1 day 29 mins
Selected

random-bred rats

It should be noted that "mongrel rats" is found primarily in translated Russian journals, erroneously. As Jennifer explains, they are "rats of no particular breed," they are randomly bred. Mongrel - Wikipedia, the free encyclopedia
https://en.wikipedia.org/wiki/Mongrel
Wikipedia
Pure breeds have been, for the most part, artificially created from random-bred populations

There are random-bred dogs, cats, etc.
Mongrel - Wikipedia, the free encyclopedia
https://en.wikipedia.org/wiki/Mongrel
Wikipedia
Pure breeds have been, for the most part, artificially created from random-bred populations

Chemical induction of prostatic tumours in random-bred rats.
www.ncbi.nlm.nih.gov/.../5...National Center for Biotechnology Information by SK Gupta - ‎1971

www.ncbi.nlm.nih.gov/.../1...National Center for Biotechnology Information by H SHAY - ‎1950 -
Proc Soc Exp Biol Med. 1950 Dec;75(3):753-4. Uniform transfer to random bred rats of

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Note added at 1 day44 mins (2015-11-14 22:31:26 GMT)
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Sorry for the Wikipedia duplication. More evidence for random-bred: Search Results

[Serotonin content in different sections of the brain, liver ...
www.ncbi.nlm.nih.gov/.../6...National Center for Biotechnology Information
by VN Zhukov - 1982
Experiments were made with white random-bred rats (males) exposed to ethanol. The content of serotonin measured by spectrofluorometry was higher in the ...
Anticancer efficacy of allogeneic vaccine modified with ...
www.ncbi.nlm.nih.gov/.../2...National Center for Biotechnology Information
MATERIALS AND METHODS: The study was performed on 74 white random-bred rats. ATV was developed on the basis of glioma 101.8 cell suspension ...
[Effect of ethanol on the concentration of enkephalins in the ...
www.ncbi.nlm.nih.gov/.../6...National Center for Biotechnology Information
by IV Burov - ‎1983 -
Radioimmunoassay was used to measure the content of leu- and met-enkephalins in white random-bred rats divided into groups according to the duration of ...
[Effect of chorionic gonadotropin on the content of ...
www.ncbi.nlm.nih.gov/.../6...National Center for Biotechnology Information
by IM Solopaeva - ‎1983 - ‎Cited by 3 - ‎Related articles
... the content of prostaglandins E + A in the liver and blood plasma of white random-bred rats with chronic hepatitis increases (both after and without castration).

You'll note that these, too, are from translated Russian publications, correctly--possibly by me during my 65-year R>E translation career! LOL!
Something went wrong...
4 KudoZ points awarded for this answer. Comment: "Thank you, Jack. According to B.Franklin, being ignorant is not so much a shame, as being unwilling to learn. "
+3
1 min

mongrel rats

:)

--------------------------------------------------
Note added at 5 mins (2015-11-13 21:52:27 GMT)
--------------------------------------------------

As in, rats of no particular breed.
Peer comment(s):
agree Anton Konashenok
3 hrs
agree Erzsébet Czopyk
10 hrs
agree Oleg Lozinskiy
10 hrs
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